FREEZING CURVES OF THE SYSTEMS BENZENE-ETHER AND BENZENE-ACETONE
نویسندگان
چکیده
منابع مشابه
Benzene Metabolism by Ethanol-, Acetone-, and Benzene-inducible Cytochrome P-450 (IIE1) in Rat and Rabbit Liver Microsomes1
Ethanol is known to exert a synergistic effect on the toxicity of benzene. In the present investigation it was found that benzene was metabolized at a rate 20-65-fold higher in liver microsomes from ethanolor acetonetreated rats than in microsomes from control animals. One high affinity site \Ka = 19 ±5 (SD) urn] and one low affinity site [K„ = 0.3 ±0.1 IIIM| for benzene metabolism were pre...
متن کاملBenzene metabolism by ethanol-, acetone-, and benzene-inducible cytochrome P-450 (IIE1) in rat and rabbit liver microsomes.
Ethanol is known to exert a synergistic effect on the toxicity of benzene. In the present investigation it was found that benzene was metabolized at a rate 20-65-fold higher in liver microsomes from ethanol- or acetone-treated rats than in microsomes from control animals. One high affinity site [Km = 19 +/- 5 (SD) microM] and one low affinity site [Km = 0.3 +/- 0.1 mM] for benzene metabolism we...
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The application of carcinogenic hydrocarbons to the skin of experimental animals has been the subject of numerous investigations since Cook and Kennaway and their associates first used dibenzanthracene in I93o. However, few observations have been published on the effect of the method of application or of the solvent for the carcinogen, upon carcinogenesis. In other publications (6-8) we have em...
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متن کاملSystems biology of human benzene exposure.
Toxicogenomic studies, including genome-wide analyses of susceptibility genes (genomics), gene expression (transcriptomics), protein expression (proteomics), and epigenetic modifications (epigenomics), of human populations exposed to benzene are crucial to understanding gene-environment interactions, providing the ability to develop biomarkers of exposure, early effect and susceptibility. Compr...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1926
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.1.183